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The Science of Spryng

  • Discover the underlying biology of osteoarthritis (OA), including how inflammatory mediators, synovial dysfunction, and extracellular matrix degradation drive progressive joint pain and mobility loss across dogs, cats, and horses.
  • Learn how joint homeostasis breaks down in OA, from changes in synovial fluid viscosity and cartilage integrity to structural and cellular alterations within the synovium that accelerate disease progression.
  • Understand the role of bioscaffolds in joint support, including how collagen-elastin-hydrogel microparticles are designed to mimic the natural extracellular matrix and interact with synovial tissues to support joint biomechanics.
  • Explore a dual-mechanism approach to joint health, combining immediate improvements in synovial fluid properties with longer-term constructive remodeling of joint tissues that may support sustained mobility and comfort.
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