Download the Science of Spryng

Discover the underlying biology of osteoarthritis (OA), including how inflammatory mediators, synovial dysfunction, and extracellular matrix degradation drive progressive joint pain and mobility loss across dogs, cats, and horses.
Learn how joint homeostasis breaks down in OA, from changes in synovial fluid viscosity and cartilage integrity to structural and cellular alterations within the synovium that accelerate disease progression.
Understand the role of bioscaffolds in joint support, including how collagen-elastin-hydrogel microparticles are designed to mimic the natural extracellular matrix and interact with synovial tissues to support joint biomechanics.
Explore a dual-mechanism approach to joint health, combining immediate improvements in synovial fluid properties with longer-term constructive remodeling of joint tissues that may support sustained mobility and comfort.

Considering Spryng for your patients?